§70.11 着色剂相关物质(Related substances)

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    　　§ 70.11   Related substances.

　　（a） Different color additives may cause similar or related pharmacological or biological effects, and, in the absence of evidence to the contrary, those that do so will be considered to have additive toxic effects.

　　（b） Food additives may also cause pharmacological or biological effects similar or related to such effects caused by color additives, and, in the absence of evidence to the contrary, those that do so will be considered as having additive toxic effects.

　　（c） Pesticide chemicals may also cause pharmacological or biological effects similar or related to such effects caused by color additives, and, in the absence of evidence to the contrary, those that do so will be considered to have additive toxic effects.

　　（d） In establishing tolerances for color additives, the Commissioner will take into consideration, among other things, the amount of any common component permitted in other color additives, in food additives, and in pesticide chemical residues as well as the similar biological activity （such as cholinesterase inhibition） produced by such substance.

　　§70.11　相关物质

　　（a）不同的着色剂可能会造成类似的或相关的药理或生理效果，那么，在缺乏相反的证据的情况下，这类着色剂应当看做具有叠加的毒性效果。

　　（b）食品添加剂也可能造成由着色剂导致的类似的或相关的效果，那么，在缺乏相反的证据的情况下，两者应当看做是具有叠加的毒性效果。

　　（c）杀虫剂也可能造成由着色剂导致的类似的或相关的效果，那么，在缺乏相反的证据的情况下，两者应当看做是具有叠加的毒性效果。

　　（d）在确定着色剂的容许使用量时，专员应当在诸多的因素中，考虑在着色剂、食品添加剂和农药化学残留物中任何共有成分的容许使用量，以及由这种物质产生的相类似的生物活性（例如乙酰胆碱酯酶抑制作用）。